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Entries in women in science (64)

Wednesday
Nov092022

Congratulations to Dr Ana Acosta!

Well done to Dr Ana Acosta, who successfully defended her PhD today! Ana tackled a challenging and exciting project on the role of HNF1A in monogenic diabetes, generating a new mouse model and validating results in primary human islets. Her work dramatically alters the way we see HNF1A in glucose homeostasis and diabetes. A very productive PhD, performed at University of Lille, with Prof Caroline Bonner, and the University of Leuven, with my team. The 20th PhD student to graduate from my lab, and one of the last from our Leuven days! Great job Dr Acosta!
Tuesday
Dec212021

2021 Golden Pipette

The Golden Pipette has a long and illustrious record. Awarded at every lab retreat in recognition of a single very cool result, the Golden Pipette has been handed down through generations of talented scientists. This year the Golden Pipette was awarded to.... Ntombizodwa Makuyana, for her exciting new approach to creating an anti-inflammatory environment in the lung. Well done Tombi, for a stunning first year PhD result!

Saturday
Oct092021

Congratulations to Ntombizodwa Makuyana

Congratulations to Ntombizodwa Makuyana, for winning the Babraham Institute prize for best poster by a first year PhD student!

A great start to a high potential PhD!

Monday
Jun212021

My Life in Science

An old talk I gave on my scientific career, with an emphasis on being a parent scientist and on my experience in seeing sexism in action in the academic career pathway:

Tuesday
Jun012021

Congratulations Dr Steffie Junius!

Congratulations Dr Steffie Junius, for achieving a successful PhD! Steffie has just completed an ambitious graduate program, studying the plasticity and fragility of regulatory T cells. It has been a pleasure watching Steffie grow into a successful scientist. Like every PhD, it had its ups and downs, its challenges and highlights, and I'm incredibly proud of how Steffie handled the entire process. I just wish I could have been there in person to celebrate her big day!
Dr Junius is now moving on to an exciting position as post-doctoral researcher at Janssen. Her major thesis work on regulatory T cell plasticity will hopefully come out soon - it is an elegant study with major implications for the design of cell therapy approaches using regulatory T cells. Well done Steffie!
Thursday
Oct082020

Congratulations to Julika Neumann!

CCongratulations to the very talented Julika Neumann, who successfully defended her application for a competitive FWO PhD fellowship!

Just starting her PhD, Julika already has several major successes under her belt, including identifying a new primary immunodeficiency (stay tuned!) and spear-heading an open science study on COVID pathology.

We anticipate more great successes from Julika during her FWO fellowship!

Sunday
Dec012019

Congratulations Dr Erika Van Nieuwenhove!

A huge round of congratulations for Dr Erika Van Nieuwenhove, who successfully defended her PhD. Erika set for gold standard for PhD defences, with an outstanding presentation and masterful question time. Erika's thesis was on inborn errors of immunity, with her PhD covering multiple new genetic mechanisms for PIDs, including mutations in ADA2 and Ikaros, plus a machine learning-driven approach to the diagnosis of JIA. The work is not yet finished either - stayed tuned for more Van Nieuwenhove papers on new genetic causes of neutropenia! A future leader in pediatric immunology and rheumatology!
Friday
Aug302019

Dr Lidia Yshii wins Golden Pipette

Congratulations to Dr Lidia Yshii for winning the 7th Golden Pipette at our joint Leuven-Cambridge lab retreat held at the Babraham.

The most elegant experiment is always a tough call at our lab retreat, but it is hard to go past a simple treatment that blocks 90% of the damage during traumatic brain injury!

Looking forward to accelerating this treatment into the translational space. 

Wednesday
Apr242019

Dokter Algoritme

Algoritmen kunnen inzichten bereiken waar een mens moeilijk toe komt. Computeralgoritmen kunnen almaar beter moeilijke diagnosen stellen, soms zelfs beter dan artsen. Immunologe Erika Van Nieuwenhove van de Leuvense tak aan het Vlaams Instituut voor Biotechnologie (VIB) en haar collega’s melden in Annals of the Rheumatic Diseases dat ze een zelflerend algoritme hebben ontwikkeld dat met bijna 90 procent zekerheid artritis bij kinderen kan vaststellen, louter op basis van een bloedtest.

Het gaat om de vaakst voorkomende vorm van reuma bij kinderen, maar omdat de ernst en de evolutie van de symptomen sterk kunnen variëren, is een diagnose stellen niet altijd gemakkelijk. Het algoritme evalueert alleen de samenstelling van het immuunsysteem van de patiënten. Het zal nuttig zijn om te bepalen welke behandeling aangewezen is.

Knack - 24 Apr. 2019 - Page 86

Thursday
Apr042019

Is the Scandinavian model the solution for STEM parents?

The Scandinavian model for parental leave is often touted as the world’s best. 12 months parental leave, split between both parents. This is a great model for a lot of careers, but is it actually a part of the solution to the issues that women face in the STEM fields?  In some cases, perhaps, but as a blanket solution I find it lacking:

1)     First, it must be stated that extended parental leave is only part of the Scandinavian model. When it was first legislated, the leave was typically taken almost exclusively by the mother, with the father just taking the mandated “Daddy’s two weeks”. Essentially, it reinforced the traditional model that put parenting on to the woman, often truncating women’s careers. This has changed substantially over the years, but those changes are due to the evolution of Scandinavian culture and the increasing normality of equality in the Scandinavian countries. Implementing just extended parental leave will not recreate the full advances seen in women’s careers across Scandinavia in the past decade

2)     Extended parental leave is ideal for workplaces where workers can be readily replaced during this period. Large employers are capable of hiring extra staff which can shift between different positions, and employees that only need days or weeks of training to get up to speed are easier to replace. Academic science generally fulfils neither of these categories. First, while universities are large, labs are essentially independent small businesses. Few if any labs are large enough to have standing rotating staff that substitute in for parental leave. Second, for scientific staff, their skills require months or years of training. As an employer, I generally write off the first 3 months of a post-doc’s time as just getting up to scratch of new techniques and the project. For a Masters student starting a PhD, often the entire first year is spent mastering the field without actual productive experiments being performed. That level of expertise is just not readily replaceable, which means the science suffers. This will then leave a negative mark on the applicants' CV beyond the one-year gap.

3)     Scientific funding and scientific projects rarely have the flexibility to make this work. Consider a PI who hires a post-doc to work on a 3 year project. One year into the project, the post-doc goes on maternity leave for a year. The PI cannot put the project on hold for a year – since the funding clock is still running. Instead they need to transfer the project to a new person. Is it fair or reasonable for that project to be transferred again when the parental leave post-doc comes back? Potentially, but it is something that needs to be solved on a case-by-case basis. Even if the funding could be put on hold for parental leave (as in some fellowships), scientific careers are built on advancing science. If the work is scooped in the meantime, original work becomes confirmatory work – which would be a negative for the lab, the PI and the post-doc.

Consider two hypothetical cases, and whether extended parental leave helps or hinders a woman’s career in science.

Scenario 1. A young female PI goes on extended parental leave. What happens to her lab? You can’t shut the lab down for a year. PIs have responsibilities to their students and post-docs, they have responsibilities to their grant funders. So either those students get shuffled to another PI, or they have to work independently (and sub-optimally), or the PI on leave actually spends a chunk of unrecognised time managing the lab remotely. After the return, authorship on papers can often become murky and grants have been spent inefficiently.

Scenario 2. A young post-doc employed on a grant goes on extended parental leave. The PI hires a replacement post-doc to continue the project (the grant and science must go on). A year later the post-doc returns and (best case scenario) the PI manages to find enough funding to keep both staff on for a year to finish up. The paper may end up with a joint-first authorship, or maybe the new post-doc was able to push things fast enough that the original post-doc becomes second author. Afterall, the year back after parental leave is hardly your most productive. There is no easy fix – the PI needs to consider the contribution of both staff members in making a decision.

In short, I think that the Scandinavian model is excellent, and an incredible advance for some careers. However the particular aspect of extended parental leave is not suitable for all people (not everyone wants it), and it can have a negative effect on STEM careers. I would suggest a more flexible approach to STEM researchers who have children. This approach would allow researchers to make the choice to take extended leave, or make the choice to stay active in their field:

  • Extended parental leave should be an option available to all
  • Implement broad structural changes that promote equality in STEM, most importantly hiring women at senior levels and normalising a healthy life balance
  • Infant daycare and before/after-hours childcare should be cheap and readily available for parents who chose that pathway.
  • A “parental sabbatical” should be available to PIs who have children, where the PI becomes excused from all teaching and committee duties for a year, but is still able to work on research
  • Grants should be automatically extended by a year if the PI has a child or if the staff paid on those grants go on leave
  • Ethics protocols, biosafety protocols, etc should be automatically extended by a year if the PI has a child or the staff working under those protocols go on leave
  • Review board decisions should be delayed by two years if a PI has a child
  • Please comment if you have additional suggestions

If you are interested in how my family handled having a child and a career in STEM, you can read an interview I had with eLife on being a scientist parent.